Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 11/20 | 0.39 |
| ▸ | ARG2 | P78540 | 11/20 | 0.39 |
| ▸ | ODC1 | P11926 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764832 | 0.80 | ARG1 (0.43) | ARG1ARG2ODC1MEN1ALDH1A1 | |
| SCHEMBL1916175 | 0.78 | ARG2 (0.53) | ARG1ARG2ODC1MEN1ALDH1A1 | |
| SCHEMBL4558784 | 0.74 | MEN1 (0.38) | ARG1ARG2ODC1MEN1ALDH1A1 | |
| SCHEMBL10656095 | 0.74 | ALDH1A1 (0.36) | ARG1ARG2ALDH1A1KDM4AKDM4C | |
| SCHEMBL1915862 | 0.74 | ARG2 (0.47) | ARG1ARG2ODC1MEN1ALDH1A1 | |
| SCHEMBL10006590 | 0.73 | ARG1 (0.69) | ARG1ARG2 | |
| SCHEMBL20978522 | 0.72 | ARG1 (0.41) | ARG1ARG2ODC1 | |
| SCHEMBL12292622 | 0.72 | ARG1 (0.67) | ARG1ARG2 | |
| SCHEMBL1916741 | 0.71 | ARG1 (0.45) | ARG1ARG2ODC1MEN1ALDH1A1 | |
| SCHEMBL14764529 | 0.71 | MEN1 (0.52) | ARG1ARG2ODC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091945-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |