Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362760 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2HSP90AA1HTTKDM4E | |
| SCHEMBL13906649 | 0.82 | CA12 (0.47) | SMN1; SMN2HTTALDH1A1POLBMIF | |
| SCHEMBL7359915 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2HSP90AA1HTTKDM4E | |
| SCHEMBL27751058 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MIFNR1H4CA12 | |
| SCHEMBL27771852 | 0.79 | ATM (0.49) | MAPTHTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27751009 | 0.79 | MEN1 (0.51) | MAPTKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3820411 | 0.77 | LMNA (0.48) | MAPTHTTALDH1A1CYP3A4MIF | |
| SCHEMBL31753129 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1POLBMIF | |
| SCHEMBL7493533 | 0.76 | MAPT (0.42) | MAPTSMN1; SMN2HSP90AA1HTTALDH1A1 | |
| SCHEMBL3596818 | 0.75 | MIF (0.43) | SMN1; SMN2POLBMIFNR1H4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997011960-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1997-04-03 | — | — | WO | disclosed |