Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.46 |
| ▸ | PROC | P04070 | 4/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723792 | 0.86 | TPSAB1 (0.46) | F2PROCTPSAB1F7F3 | |
| SCHEMBL8727289 | 0.85 | F2 (0.47) | F2PROCTPSAB1F7 | |
| SCHEMBL7355230 | 0.71 | F2 (0.44) | F2PROCTMPRSS6 | |
| SCHEMBL7362891 | 0.71 | F2 (0.44) | F2PROCF7F3TMPRSS6 | |
| SCHEMBL7362804 | 0.70 | F2 (0.44) | F2PROCF7F3KLKB1 | |
| SCHEMBL7050535 | 0.70 | F2 (0.44) | F2PROCTPSAB1 | |
| SCHEMBL8023156 | 0.69 | F2 (0.48) | F2PROCTMPRSS6 | |
| SCHEMBL8019344 | 0.69 | ITGB3 (0.44) | F2PROCTMPRSS6 | |
| SCHEMBL7708062 | 0.65 | F2 (0.57) | F2PROCTPSAB1F7TMPRSS6 | |
| SCHEMBL7316950 | 0.64 | F2 (0.51) | F2PROCTPSAB1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |