Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.53 |
| ▸ | F2 | P00734 | 16/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6006300 | 0.80 | LTA4H (0.56) | LTA4H | |
| SCHEMBL6005586 | 0.72 | LTA4H (0.53) | LTA4H | |
| SCHEMBL7360130 | 0.72 | F10 (0.58) | F10F2PRSS1 | |
| SCHEMBL7365375 | 0.71 | F10 (0.56) | F10F2PRSS1 | |
| SCHEMBL8346836 | 0.70 | F10 (0.49) | F10F2PRSS1LTA4H | |
| SCHEMBL7455464 | 0.68 | F10 (1.00) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8343413 | 0.67 | F2 (0.48) | F10F2PRSS1LTA4H | |
| SCHEMBL1624623 | 0.67 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL7460126 | 0.67 | F10 (0.63) | F10F2PRSS1 | |
| SCHEMBL5691956 | 0.66 | ALDH1A1 (0.59) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |