Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.56 |
| ▸ | F2 | P00734 | 15/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360130 | 0.95 | F10 (0.58) | F10F2PRSS1 | |
| SCHEMBL31477970 | 0.83 | KMT2A (0.52) | ALDH1A1 | |
| SCHEMBL31477951 | 0.75 | CNR2 (0.52) | ALDH1A1 | |
| Methyl Benzoate SCHEMBL7359033 | 0.74 | F10 (0.61) | F10F2PRSS1 | |
| SCHEMBL8343396 | 0.72 | F10 (0.84) | F10F2PRSS1 | |
| SCHEMBL7362905 | 0.71 | F10 (0.53) | F10F2PRSS1 | |
| SCHEMBL7454445 | 0.71 | F10 (1.00) | F10F2PRSS1 | |
| SCHEMBL7310631 | 0.70 | BCAT2 (0.49) | ALDH1A1 | |
| Benzamidine SCHEMBL7366537 | 0.69 | F10 (0.67) | F10F2PRSS1 | |
| Methyl Benzoate SCHEMBL7560351 | 0.69 | F2 (0.55) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |