Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | MMP3 | P08254 | 13/20 | 0.47 |
| ▸ | MMP1 | P03956 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363089 | 1.00 | CASP3 (0.51) | CASP3MMP3MMP1MMP2 | |
| SCHEMBL6957869 | 0.92 | MMP3 (0.45) | CASP3MMP3MMP1MMP2 | |
| SCHEMBL8710650 | 0.92 | MMP3 (0.45) | CASP3MMP3MMP1MMP2 | |
| SCHEMBL6961469 | 0.88 | MMP3 (0.46) | CASP3MMP3MMP1MMP2 | |
| SCHEMBL6961474 | 0.88 | MMP3 (0.46) | CASP3MMP3MMP1MMP2 | |
| SCHEMBL7470774 | 0.87 | MMP3 (0.54) | MMP3MMP1MMP2 | |
| SCHEMBL7360661 | 0.87 | MMP3 (0.54) | MMP3MMP1MMP2 | |
| SCHEMBL7358844 | 0.84 | MMP3 (0.59) | MMP3MMP1MMP2 | |
| SCHEMBL7358853 | 0.84 | MMP3 (0.59) | MMP3MMP1MMP2 | |
| SCHEMBL7394814 | 0.83 | MMP3 (0.46) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |