Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710650 | 1.00 | MMP3 (0.45) | MMP3MMP1CASP3MMP2MEN1 | |
| SCHEMBL7363089 | 0.92 | CASP3 (0.51) | MMP3MMP1CASP3MMP2 | |
| SCHEMBL7363092 | 0.92 | CASP3 (0.51) | MMP3MMP1CASP3MMP2 | |
| SCHEMBL7360661 | 0.85 | MMP3 (0.54) | MMP3MMP1MMP2 | |
| SCHEMBL7470774 | 0.85 | MMP3 (0.54) | MMP3MMP1MMP2 | |
| SCHEMBL6961469 | 0.84 | MMP3 (0.46) | MMP3MMP1CASP3MMP2LMNA | |
| SCHEMBL6961474 | 0.84 | MMP3 (0.46) | MMP3MMP1CASP3MMP2LMNA | |
| SCHEMBL6962422 | 0.83 | MEN1 (0.60) | MMP3MMP1CASP3MMP2MEN1 | |
| SCHEMBL8708271 | 0.83 | MEN1 (0.60) | MMP3MMP1CASP3MMP2MEN1 | |
| SCHEMBL7358844 | 0.81 | MMP3 (0.59) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |