SCHEMBL7363474

SCHEMBL7363474

CCCCCCOc1ccccc1S(=O)(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
MEN1 O00255 1/20 0.51
NR1I2 O75469 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
MAPT P10636 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
KMT2A Q03164 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
PTPN1 P18031 1/20 0.42
CYSLTR2 Q9NS75 2/20 0.42
CYSLTR1 Q9Y271 2/20 0.42
S1PR3 Q99500 1/20 0.42
THRA P10827 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10652106 1.00 LMNA (0.51) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL10945251 1.00 LMNA (0.51) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL3371631 0.98 CYP3A4 (0.49) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL995712 0.93 CYP1A2 (0.51) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL7356282 0.88 NPC1 (0.43) LMNAMEN1MAPTHTR2BKMT2A
SCHEMBL10569238 0.86 CHRM2 (0.44) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL727321 0.84 LMNA (0.55) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL179760 0.84 LMNA (0.55) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL8770368 0.84 LMNA (0.55) LMNAMEN1NR1I2CHRM2CYP3A4
SCHEMBL7520068 0.84 LMNA (0.55) LMNAMEN1NR1I2CHRM2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778839-B1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1998-12-23 EP disclosed
US-5824679-A Phosphanoxides--preparation and use BOEHRINGER MANNHEIM GMBH (DE) 1998-10-20 US disclosed
EP-0778839-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1997-06-18 EP disclosed
WO-1996006849-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1996-03-07 WO disclosed