SCHEMBL995712

SCHEMBL995712

CCCCOc1ccccc1S(=O)(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
L3MBTL1 Q9Y468 3/20 0.44
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 3/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADRA2A P08913 1/20 0.43
OPRK1 P41145 1/20 0.43
HTR2B P41595 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
TSHR P16473 3/20 0.41
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371631 0.95 CYP3A4 (0.49) CYP1A2CYP2C9CYP2C19L3MBTL1GAA
SCHEMBL10652106 0.93 LMNA (0.51) CYP1A2CYP2C9CYP2C19MAPTKMT2A
SCHEMBL7363474 0.93 LMNA (0.51) CYP1A2CYP2C9CYP2C19MAPTKMT2A
SCHEMBL10945251 0.93 LMNA (0.51) CYP1A2CYP2C9CYP2C19MAPTKMT2A
SCHEMBL7356282 0.91 NPC1 (0.43) CYP1A2CYP2C9CYP2C19L3MBTL1GAA
SCHEMBL1896177 0.84 CYP1A2 (0.53) CYP1A2CYP2C9CYP2C19L3MBTL1GAA
SCHEMBL16541588 0.84 CYP1A2 (0.53) CYP1A2CYP2C9CYP2C19L3MBTL1GAA
SCHEMBL8726763 0.84 TRPV4 (0.55) L3MBTL1GAAMAPTTSHRCA12
SCHEMBL31511099 0.84 TRPV4 (0.55) L3MBTL1GAAMAPTTSHRCA12
SCHEMBL1334803 0.83 CYP1A2 (0.51) CYP1A2CYP2C9CYP2C19L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444258-B Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2024-08-20 CN claimed
CN-116444258-A Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2023-07-18 CN claimed
CN-116444258-B Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2024-08-20 CN disclosed
CN-116444258-B Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2024-08-20 CN disclosed
CN-116444258-A Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2023-07-18 CN disclosed
CN-116444258-A Foamed ceramic prepared from steel slag and red mud and process thereof 江门市俞嘉科技有限公司 2023-07-18 CN disclosed
EP-2456435-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE The Board of Trustees of The Leland Stanford Junior University (US) 2012-05-30 EP disclosed
WO-2011011514-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-01-27 WO disclosed
EP-1406884-A1 ARYLSUSFONAMIDE COMPOUNDS FOR THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS-DISORDERS BIOVITRUM AB (SE) 2004-04-14 EP disclosed
EP-1303485-A1 PYRROLIDINE DERIVATIVES AS INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME F. HOFFMANN-LA ROCHE AG (CH) 2003-04-23 EP disclosed
EP-1283831-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 BIOVITRUM AB (SE) 2003-02-19 EP disclosed
EP-0927161-A1 SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1999-07-07 EP disclosed
EP-0778839-B1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1998-12-23 EP disclosed
US-5824679-A Phosphanoxides--preparation and use BOEHRINGER MANNHEIM GMBH (DE) 1998-10-20 US disclosed
WO-1998008815-A1 SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1998-03-05 WO disclosed
EP-0778839-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1997-06-18 EP disclosed
WO-1996006849-A1 NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS BOEHRINGER MANNHEIM GMBH (DE) 1996-03-07 WO disclosed
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3932419-A QUINOLINE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed