Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365129 | 0.83 | DPP4 (0.34) | DPP4DPP7RIPK1AGBL2DPP9 | |
| SCHEMBL7355560 | 0.83 | RIPK1 (0.43) | DPP4DPP7RIPK1PKM | |
| SCHEMBL28791404 | 0.80 | PPARG (0.42) | DPP4DPP7 | |
| SCHEMBL451846 | 0.76 | SLC6A4 (0.36) | DPP4AGBL2DPP9 | |
| SCHEMBL441589 | 0.76 | SLC6A4 (0.36) | DPP4AGBL2DPP9 | |
| SCHEMBL13647174 | 0.76 | SLC6A4 (0.39) | DPP4 | |
| SCHEMBL5971811 | 0.75 | TRPA1 (0.50) | — | |
| SCHEMBL6297885 | 0.74 | NPSR1 (0.42) | MEP1BAGBL2FFAR1FFAR4 | |
| SCHEMBL8240380 | 0.73 | SLC6A4 (0.40) | MEP1BRIPK1PKM | |
| SCHEMBL438798 | 0.73 | HTR2A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |