Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355560 | 0.84 | RIPK1 (0.43) | DPP4DPP7RIPK1PKMACE2 | |
| SCHEMBL7363479 | 0.83 | MEP1B (0.37) | DPP4DPP7RIPK1AGBL2DPP9 | |
| SCHEMBL7364355 | 0.79 | CYP4F2 (0.42) | — | |
| SCHEMBL26404184 | 0.79 | GABRA1 (0.39) | AGBL2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13548272 | 0.76 | MAPT (0.39) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6297613 | 0.75 | FFAR1 (0.37) | AGBL2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5971811 | 0.74 | TRPA1 (0.50) | TRPA1 | |
| SCHEMBL6441169 | 0.73 | MAPT (0.39) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31085527 | 0.72 | IDO1 (0.40) | — | |
| SCHEMBL3309883 | 0.72 | IDO1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |