Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369651 | 0.86 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2PARP1LMNA | |
| SCHEMBL7363561 | 0.85 | PLK4 (0.42) | RAB9ANPC1SMN1; SMN2PARP1HSD17B10 | |
| SCHEMBL4440941 | 0.85 | PARP1 (0.46) | RAB9ANPC1SMN1; SMN2PARP1HSD17B10 | |
| SCHEMBL8648025 | 0.78 | PARP1 (0.67) | PARP1CDK9DYRK1A | |
| SCHEMBL14347043 | 0.78 | DDAH1 (0.46) | PARP1HSD17B10MAPK1 | |
| SCHEMBL3429444 | 0.75 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL7003014 | 0.75 | PLK4 (0.45) | RAB9ASMN1; SMN2PARP1HSD17B10LMNA | |
| SCHEMBL1552751 | 0.74 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL8568575 | 0.73 | SMN1; SMN2 (0.49) | RAB9ANPC1SMN1; SMN2PARP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8568583 | 0.73 | SMN1; SMN2 (0.49) | RAB9ANPC1SMN1; SMN2HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934307-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1999-08-11 | — | — | EP | claimed |
| WO-1997048697-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1997-12-24 | — | — | WO | claimed |