Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358222 | 0.86 | GPR119 (0.51) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL8473886 | 0.84 | GPR119 (0.68) | GPR119NAMPTALDH1A1 | |
| SCHEMBL8473888 | 0.84 | GPR119 (0.68) | GPR119NAMPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7365888 | 0.82 | DRD2 (0.44) | ALDH1A1CHRM4 | |
| SCHEMBL4513559 | 0.81 | GPR119 (0.70) | GPR119NAMPTLMNATP53CHRM4 | |
| SCHEMBL8473977 | 0.81 | GPR119 (0.46) | GPR119ALDH1A1CHRM4KDM4EPKM | |
| SCHEMBL4510819 | 0.80 | GPR119 (0.71) | GPR119 | |
| SCHEMBL8473456 | 0.79 | GPR119 (0.49) | GPR119NAMPTALDH1A1KDM4EPKM | |
| SCHEMBL8473460 | 0.79 | GPR119 (0.49) | GPR119NAMPTALDH1A1KDM4EPKM | |
| SCHEMBL9409650 | 0.78 | CHRM4 (0.54) | GPR119NAMPTLMNATP53CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |