Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355509 | 0.99 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7269481 | 0.84 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7357182 | 0.82 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7360016 | 0.81 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8084932 | 0.81 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8088457 | 0.80 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7355171 | 0.79 | ABCC9 (0.46) | ABCC9CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL8085269 | 0.77 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8076956 | 0.77 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8088949 | 0.77 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | disclosed |
| EP-0363883-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1990-04-18 | — | — | EP | disclosed |