Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.53 |
| ▸ | ITGAL | P20701 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367820 | 0.90 | FPR2 (0.57) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL7359906 | 0.85 | ECE1 (0.60) | ECE1ACE | |
| SCHEMBL7362146 | 0.84 | ADRB3 (0.45) | ECE1 | |
| SCHEMBL4193799 | 0.79 | ECE1 (0.67) | ECE1ACE | |
| SCHEMBL7361137 | 0.78 | ACE (0.60) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL7365431 | 0.78 | ACE (0.60) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL7367496 | 0.77 | ALOX15 (0.50) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL7361908 | 0.77 | ALOX15 (0.50) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL7366298 | 0.76 | ITGB2 (0.50) | ECE1ITGB2ICAM1ITGALACE | |
| SCHEMBL5123003 | 0.76 | ALOX15 (0.67) | ECE1ITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888341-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-01-07 | — | — | EP | claimed |
| WO-1997032874-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-09-12 | — | — | WO | claimed |
| EP-0888341-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032874-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-09-12 | — | — | WO | disclosed |