Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358636 | 0.91 | ALPL (0.47) | F2ALPLMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL7373765 | 0.88 | SLC22A12 (0.52) | F2SLC22A12ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL7365762 | 0.85 | F2 (0.44) | F2SLC22A12ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL7359257 | 0.75 | F2 (0.35) | F2 | |
| SCHEMBL8732207 | 0.73 | F2 (0.37) | F2MEN1KMT2A | |
| SCHEMBL7373467 | 0.73 | F2 (0.61) | F2ALPLALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7479980 | 0.70 | F2 (0.34) | F2SMN1; SMN2 | |
| SCHEMBL5866168 | 0.69 | F2 (0.48) | F2SLC22A12ALDH1A1 | |
| SCHEMBL7928521 | 0.68 | AR (0.55) | F2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8649933 | 0.66 | F2 (0.60) | F2ALPLALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778839-B1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |
| EP-0778839-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006849-A1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |