SCHEMBL8732207

SCHEMBL8732207

CCCOc1ccccc1S(=O)(=O)N(C(=O)P(C)(C)=O)c1cc(C)cc(OCC#N)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F2 P00734 10/20 0.37
KAT6A Q92794 7/20 0.34
GRM5 P41594 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SREBF1 P36956 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
CTRC Q99895 2/20 0.31
PRSS2 P07478 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7359257 0.79 F2 (0.35) F2
SCHEMBL7479980 0.74 F2 (0.34) F2GRM5
SCHEMBL7364235 0.73 F2 (0.47) F2MEN1KMT2A
SCHEMBL7363720 0.71 F2 (0.34) F2KAT6AMEN1KMT2ACTRC
SCHEMBL8728793 0.68 F2 (0.41) F2
SCHEMBL7357199 0.66 BRPF1 (0.34) F2KAT6A
SCHEMBL7359565 0.66 F2 (0.39) F2KAT6ACTRCPRSS2
SCHEMBL7358636 0.65 ALPL (0.47) F2KAT6AMEN1KMT2A
SCHEMBL7373765 0.62 SLC22A12 (0.52) F2MEN1KMT2A
SCHEMBL7537667 0.61 F2 (0.39) F2CTRCPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5824679-A Phosphanoxides--preparation and use BOEHRINGER MANNHEIM GMBH (DE) 1998-10-20 US disclosed