Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | DNM2 | P50570 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357755 | 0.81 | MCHR1 (0.43) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL2369879 | 0.80 | DNM2 (0.49) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL4908497 | 0.80 | KDM4E (0.38) | MCHR1KDM4E | |
| SCHEMBL25920566 | 0.79 | MCHR1 (0.42) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL25920567 | 0.77 | CNR1 (0.45) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL1178837 | 0.71 | MCHR1 (0.45) | MCHR1ADRA2AHRH1ADRA1AHTR2B | |
| SCHEMBL1334607 | 0.69 | GRM5 (0.39) | DNM2CNR1KCNH2AURKBKDM4E | |
| SCHEMBL1334609 | 0.69 | GRM5 (0.39) | DNM2CNR1KCNH2AURKBKDM4E | |
| SCHEMBL2276674 | 0.69 | PLK4 (0.46) | DNM2KDM4EPTGS2CYP1A2ATM | |
| SCHEMBL10285741 | 0.69 | MAPT (0.46) | KDM4ELMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027826-A1 | NOVEL PYRIMIDINES, THE PRODUCTION THEREOF AND THEIR USE | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-05-18 | — | — | WO | disclosed |