Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920566 | 0.86 | MCHR1 (0.42) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL25925683 | 0.83 | CNR1 (0.45) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL1178837 | 0.80 | MCHR1 (0.45) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL18036085 | 0.79 | ALDH1A1 (0.46) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL7364277 | 0.77 | MCHR1 (0.40) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL7357755 | 0.77 | MCHR1 (0.43) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL2713731 | 0.75 | HSD17B10 (0.49) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL2369879 | 0.74 | DNM2 (0.49) | CNR1KCNH2AURKBMCHR1ADRA2A | |
| SCHEMBL21200772 | 0.72 | RBP4 (0.46) | KDM4EALDH1A1MAPTPKMMEN1 | |
| SCHEMBL2715951 | 0.72 | CYP1A2 (0.55) | SMN1; SMN2KDM4EALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | CNR1 4223/4885KCNH2 4579/4885AURKB 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.