⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359542 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL7352189 | 0.64 | PREP (0.38) | — | |
| SCHEMBL9791383 | 0.62 | CNR2 (0.32) | — | |
| SCHEMBL7357083 | 0.58 | MAPT (0.31) | — | |
| SCHEMBL11497279 | 0.56 | GSK3B (0.33) | — | |
| SCHEMBL7322434 | 0.55 | PREP (0.48) | — | |
| SCHEMBL11419182 | 0.54 | ACE (0.35) | — | |
| SCHEMBL7539427 | 0.54 | HTR1A (0.33) | — | |
| SCHEMBL3987732 | 0.52 | ALDH1A1 (0.78) | — | |
| SCHEMBL3980275 | 0.52 | MAPT (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |