Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364484 | 0.90 | ANPEP (0.50) | ANPEP | |
| SCHEMBL10790065 | 0.89 | MME (0.42) | MMEANPEPKMT2A | |
| SCHEMBL10790731 | 0.88 | ANPEP (0.49) | ANPEP | |
| SCHEMBL10790739 | 0.88 | ANPEP (0.49) | ANPEP | |
| SCHEMBL7364582 | 0.88 | MME (0.57) | MMEANPEP | |
| SCHEMBL7361616 | 0.86 | FOLH1 (0.48) | EPHX2PPARGANPEP | |
| SCHEMBL10790362 | 0.81 | FOLH1 (0.43) | — | |
| SCHEMBL7361926 | 0.81 | ACE (0.54) | MME | |
| SCHEMBL10790734 | 0.80 | ANPEP (0.46) | ANPEPMEN1KMT2A | |
| SCHEMBL7367028 | 0.77 | FOLH1 (0.55) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |