Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.57 |
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364484 | 0.92 | ANPEP (0.50) | ANPEP | |
| SCHEMBL10790731 | 0.91 | ANPEP (0.49) | ANPEP | |
| SCHEMBL10790739 | 0.91 | ANPEP (0.49) | ANPEP | |
| SCHEMBL7364462 | 0.88 | EPHX2 (0.48) | MMEANPEP | |
| SCHEMBL10790065 | 0.86 | MME (0.42) | MMEANPEP | |
| SCHEMBL8861599 | 0.84 | MME (0.79) | MMEANPEP | |
| SCHEMBL10790734 | 0.82 | ANPEP (0.46) | ANPEP | |
| SCHEMBL8861591 | 0.82 | MME (0.60) | MMEACE | |
| SCHEMBL7367028 | 0.80 | FOLH1 (0.55) | ANPEP | |
| SCHEMBL7371290 | 0.80 | MMEL1 (0.74) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |