Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365434 | 0.88 | GPR119 (0.53) | GPR119ATMMAPTMAPK1TP53 | |
| SCHEMBL12814098 | 0.88 | NPSR1 (0.55) | GPR119ALDH1A1ATMMAPTMAPK1 | |
| SCHEMBL8226185 | 0.83 | L3MBTL1 (0.55) | GPR119ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8259577 | 0.83 | TSHR (0.52) | GPR119ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8661802 | 0.83 | NPSR1 (0.51) | GPR119ALDH1A1ATMMAPTHTT | |
| SCHEMBL8325276 | 0.83 | NPSR1 (0.51) | GPR119ALDH1A1ATMMAPTHTT | |
| SCHEMBL18551089 | 0.83 | CKS1B (0.47) | GPR119 | |
| SCHEMBL32688003 | 0.82 | GPR119 (0.52) | GPR119ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL5683300 | 0.81 | GPR119 (0.53) | GPR119ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL674604 | 0.81 | GPR119 (0.56) | GPR119ALDH1A1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |