Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19750987 | 0.89 | BACE1 (0.56) | MMEBACE1ACEMMP2 | |
| SCHEMBL30051551 | 0.85 | MME (0.58) | GNPATMMEACE | |
| SCHEMBL31668884 | 0.85 | BACE1 (0.60) | MMEBACE1MMP1 | |
| SCHEMBL30051314 | 0.83 | LTA4H (0.56) | GNPATMMELTA4HACE | |
| SCHEMBL26169838 | 0.83 | MME (0.59) | MMEACE | |
| SCHEMBL7405637 | 0.83 | MMP1 (0.59) | MMP1FCER2MMP2 | |
| Mdl-28170 SCHEMBL30873029 | 0.83 | MME (0.61) | MMEACE | |
| Mdl-28170 SCHEMBL7335375 | 0.83 | MME (0.61) | MMEACE | |
| Mdl-28170 SCHEMBL11370994 | 0.83 | MME (0.61) | MMEACE | |
| SCHEMBL30385107 | 0.82 | GNPAT (0.52) | GNPATMMEBACE1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | disclosed |