Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 0.62 |
| ▸ | CASP7 | P55210 | 5/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | CASP9 | P55211 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234582 | 0.91 | ALDH1A1 (0.59) | CASP3CASP7CTSLCTSBCTSS | |
| SCHEMBL18740358 | 0.90 | CASP3 (0.58) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL6269817 | 0.90 | CTSD (0.59) | CASP3CASP7CTSLCTSBREN | |
| SCHEMBL17326941 | 0.87 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL4420464 | 0.87 | CASP3 (0.67) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL7383742 | 0.87 | CASP3 (0.67) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL7269151 | 0.85 | ALDH1A1 (0.60) | CASP3CASP7CTSLCTSBCTSS | |
| SCHEMBL3058668 | 0.85 | ECE1 (0.61) | CASP3CASP7CTSLCTSBCTSS | |
| SCHEMBL25287172 | 0.85 | ECE1 (0.61) | CASP3CASP7CTSLCTSBCTSS | |
| SCHEMBL21845032 | 0.85 | CASP3 (0.65) | CASP3CASP7CASP1CASP9CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | disclosed |