Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746594 | 0.90 | MTNR1A (0.57) | ALDH1A1MTNR1AMTNR1BSLC2A1PLAAT3 | |
| SCHEMBL10163435 | 0.87 | MTNR1A (0.62) | ALDH1A1MTNR1AMTNR1BSLC2A1PLAAT3 | |
| SCHEMBL7365371 | 0.86 | MTNR1A (0.61) | ALDH1A1MTNR1AMTNR1BSLC2A1PLAAT3 | |
| SCHEMBL10604591 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MTNR1AMTNR1BSLC2A1HPGD | |
| SCHEMBL9269689 | 0.83 | KMT2A (0.59) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL25773443 | 0.82 | MTNR1A (0.69) | ALDH1A1MTNR1AMTNR1BPLAAT3PLAAT5 | |
| SCHEMBL12707505 | 0.82 | SLC2A1 (0.58) | ALDH1A1MTNR1AMTNR1BSLC2A1HPGD | |
| SCHEMBL17821665 | 0.82 | MTNR1A (0.65) | ALDH1A1MTNR1AMTNR1BPLAAT3PLAAT5 | |
| SCHEMBL2746596 | 0.81 | MTNR1A (0.56) | ALDH1A1MTNR1AMTNR1BSLC2A1ABCB1 | |
| SCHEMBL13139208 | 0.81 | MTNR1A (0.78) | ALDH1A1MTNR1AMTNR1BPLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |