Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536952 | 0.78 | KDM4E (0.41) | LTA4HALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL5535359 | 0.77 | KDM4E (0.37) | LTA4HALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9773303 | 0.77 | KDM4E (0.37) | LTA4HALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL5262577 | 0.71 | DAO (0.31) | — | |
| SCHEMBL10406683 | 0.69 | CYP2A6 (0.47) | ALDH1A1HPGDHSD17B10TDO2L3MBTL1 | |
| SCHEMBL9773372 | 0.69 | CYP2A6 (0.44) | ALDH1A1HPGDKDM4ERAB9AMEN1 | |
| SCHEMBL8879879 | 0.69 | LTA4H (0.42) | LTA4HALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11983234 | 0.69 | RAB9A (0.44) | LTA4HALDH1A1MAPTHPGDGAA | |
| SCHEMBL10407470 | 0.68 | NPC1 (0.36) | ALDH1A1HPGDGAATSHRSMN1; SMN2 | |
| SCHEMBL11196784 | 0.68 | LTA4H (0.38) | LTA4HALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010090-A | N-(butenyl substituted) azaheterocyclic carboxylic acids | NOVO NORDISK A/S. (DK) | 1991-04-23 | — | — | US | disclosed |
| EP-0236342-A1 | AMINO ACID DERIVATIVES. | NOVO INDUSTRI AS (DK) | 1987-09-16 | — | — | EP | disclosed |
| WO-1987000171-A1 | AMINO ACID DERIVATIVES | NOVO INDUSTRI A/S (DK) | 1987-01-15 | — | — | WO | disclosed |