Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823971 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL5535359 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL9773303 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL7364550 | 0.78 | LTA4H (0.39) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL8813597 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL3352373 | 0.74 | MAPT (0.41) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL8812142 | 0.73 | CHRM2 (0.38) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL8665476 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL22734783 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL3176511 | 0.68 | LTA4H (0.40) | KDM4EALDH1A1HSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543930-A1 | ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003421-A2 | ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |