SCHEMBL7364561

SCHEMBL7364561

Cc1ccc(S(=O)(=O)NC#N)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
ALDH1A1 P00352 8/20 0.55
TDP1 Q9NUW8 5/20 0.55
HPGD P15428 4/20 0.55
CYP2C9 P11712 4/20 0.55
CYP2C19 P33261 4/20 0.55
MAPT P10636 4/20 0.55
KDM4E B2RXH2 3/20 0.55
CYP1A2 P05177 3/20 0.55
CYP3A4 P08684 3/20 0.55
CYP2D6 P10635 3/20 0.55
ALOX12 P18054 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78504 0.81 GAA (0.59) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL9805292 0.79 GAA (0.57) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL25340319 0.79 IDO1 (0.57) GAACA1CA2MMP1MMP2
SCHEMBL3237620 0.79 GAA (0.57) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL8645355 0.79 CA1 (0.55) SMN1; SMN2CA1CA2MMP1MMP2
SCHEMBL299247 0.78 CA1 (0.52) SMN1; SMN2CA1CA2MMP1MMP2
SCHEMBL967916 0.76 ALDH1A1 (0.63) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL250756 0.76 GAA (0.64) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL7627224 0.75 ALDH1A1 (0.72) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL187561 0.75 GAA (0.70) GAASMN1; SMN2CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700786-A High-glass transition temperature high-dielectric polyaryl ether nitrile composite material and preparation method and application thereof 西南民族大学 2024-03-15 CN claimed
CN-117700786-A High-glass transition temperature high-dielectric polyaryl ether nitrile composite material and preparation method and application thereof 西南民族大学 2024-03-15 CN disclosed
CN-111533694-B Synthetic method of 2-imido hydantoin compound 河南牧业经济学院 2023-03-14 CN disclosed
WO-1992008464-A1 SUBSTITUTED UREA AND RELATED CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-05-29 WO disclosed