Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805292 | 0.81 | GAA (0.57) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL3237620 | 0.81 | GAA (0.57) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL7364561 | 0.81 | GAA (0.57) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL9135655 | 0.78 | MMP2 (0.57) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL6934611 | 0.78 | CA1 (0.57) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL423687 | 0.78 | CA2 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL423264 | 0.78 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5335389 | 0.78 | MMP2 (0.61) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL210772 | 0.77 | CA1 (0.54) | SMN1; SMN2CA1CA2MMP1MMP2 | |
| SCHEMBL187561 | 0.77 | GAA (0.70) | GAASMN1; SMN2CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3280 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-3054958-B1 | NEW PRADIMICIN DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY KINETOPLASTIDS | UNIV LEUVEN KATH (BE) | 2020-06-03 | — | — | EP | claimed |
| EP-3323414-A1 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| EP-2621902-B1 | 3-AZABICYCLO[3.1.0]HEXANE COMPOUNDS USEFUL FOR THE TREATMENT OF CNS DISORDERS | PANACEA BIOTEC LTD (IN) | 2017-04-12 | — | — | EP | claimed |
| US-20160243140-A1 | NEW PRADIMICIN DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY KINETOPLASTIDS | KATHOLIEKE UNIVERSITEIT LEUVEN (AU) | 2016-08-25 | — | — | US | claimed |
| EP-3054958-A1 | NEW PRADIMICIN DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY KINETOPLASTIDS | Katholieke Universiteit Leuven (BE) | 2016-08-17 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-9133116-B2 | Bicyclic compounds | PANACEA BIOTEC LTD. (IN) | 2015-09-15 | — | — | US | claimed |
| WO-2015051422-A1 | NEW PRADIMICIN DERIVATIVES FOR THE TREATMENT OF DISEASES CAUSED BY KINETOPLASTIDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-04-16 | — | — | WO | claimed |
| US-20030216571-A1 | Antiallergens; antiinflammatory agents | UBE INDUSTRIES, LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1254897-A1 | TRICYCLIC COMPOUNDS | Ube Industries, Ltd. (JP) | 2002-11-06 | — | — | EP | claimed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | claimed |
| EP-0626956-B1 | QUINOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| US-5530124-A | Method for preparing cyclic ureas and their use for the synthesis of HIV protease inhibitors | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-06-25 | — | — | US | claimed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | claimed |
| US-5360928-A | Synthesis and use of amino acid fluorides as peptide coupling reagents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-11-01 | — | — | US | claimed |
| EP-0428132-B1 | PRADIMICIN DERIVATIVES | Bristol-Myers Squibb Company (US) | 1993-08-04 | — | — | EP | claimed |
| EP-0428132-A1 | Pradimicin derivatives | Bristol-Myers Squibb Company (US) | 1991-05-22 | — | — | EP | claimed |