Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7366559 | 0.86 | DRD2 (0.48) | DRD2DRD3POLBDRD4GAA | |
| Hydrochloric Acid SCHEMBL8479138 | 0.86 | THRB (0.46) | HRH3ALDH1A1HPGDKMT2A | |
| SCHEMBL7366116 | 0.84 | ITGB3 (0.51) | DRD2DRD3HRH3MAPK1 | |
| Hydrochloric Acid SCHEMBL7361494 | 0.83 | ITGB3 (0.50) | DRD2DRD3HRH3MAPK1 | |
| SCHEMBL7369000 | 0.82 | SMN1; SMN2 (0.44) | DRD2DRD3HTR1AHTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL8473847 | 0.82 | SMN1; SMN2 (0.47) | DRD2DRD3HTR1AHTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL8473946 | 0.81 | SMN1; SMN2 (0.46) | DRD2DRD3HTR1AHTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL8477708 | 0.81 | SMN1; SMN2 (0.46) | DRD2DRD3HTR1AHTR2AHRH3 | |
| Hydrochloric Acid SCHEMBL8477389 | 0.80 | ATM (0.42) | DRD2DRD3HTR1AHTR2APOLB | |
| SCHEMBL7397460 | 0.79 | DRD2 (0.47) | DRD2DRD3HTR1ACHRM4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |