Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364893 | 1.00 | MME (0.52) | MMEFOLH1PSMB5LTA4HACE | |
| SCHEMBL7363529 | 0.90 | BIRC2 (0.54) | PSMB5CTSK | |
| SCHEMBL7363526 | 0.90 | BIRC2 (0.54) | PSMB5CTSK | |
| SCHEMBL5099185 | 0.86 | MME (0.54) | MMEFOLH1LTA4HACECTSK | |
| SCHEMBL5099195 | 0.86 | MME (0.54) | MMEFOLH1LTA4HACECTSK | |
| SCHEMBL7359157 | 0.82 | PSMB1 (0.50) | PSMB5CTSKCAPN1 | |
| SCHEMBL7272374 | 0.82 | MME (0.58) | MMEFOLH1LTA4HACE | |
| SCHEMBL8078351 | 0.82 | MME (0.58) | MMEFOLH1LTA4HACE | |
| SCHEMBL21759695 | 0.80 | SMN1; SMN2 (0.63) | MMELTA4HACE | |
| SCHEMBL4268532 | 0.80 | SMN1; SMN2 (0.63) | MMELTA4HACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |