Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363526 | 1.00 | BIRC2 (0.54) | BIRC2PSMB5CTSKTAS1R3TAS1R1 | |
| SCHEMBL7364893 | 0.90 | MME (0.52) | PSMB5CTSK | |
| SCHEMBL7364890 | 0.90 | MME (0.52) | PSMB5CTSK | |
| SCHEMBL13611959 | 0.80 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL14609392 | 0.80 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL3978105 | 0.80 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL26994877 | 0.80 | HDAC1 (0.62) | — | |
| SCHEMBL31506111 | 0.80 | HDAC1 (0.62) | — | |
| SCHEMBL7359157 | 0.80 | PSMB1 (0.50) | PSMB5CTSKCTSLCTSS | |
| SCHEMBL31506178 | 0.79 | HDAC1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |