Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.46 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.46 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.46 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.46 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364890 | 0.82 | MME (0.52) | PSMB5CTSKCAPN1 | |
| SCHEMBL7364893 | 0.82 | MME (0.52) | PSMB5CTSKCAPN1 | |
| SCHEMBL10591376 | 0.80 | CAPN1 (0.57) | PSMB1CTSKCTSLCTSSCAPN1 | |
| SCHEMBL7363526 | 0.80 | BIRC2 (0.54) | PSMB5CTSKCTSLCTSS | |
| SCHEMBL7363529 | 0.80 | BIRC2 (0.54) | PSMB5CTSKCTSLCTSS | |
| SCHEMBL27429302 | 0.78 | PSMB1 (0.67) | PSMB1CTSKCTSLCTSSCAPN1 | |
| SCHEMBL7267407 | 0.76 | PSMB1 (0.70) | PSMB1CTSKCTSLCTSSCAPN1 | |
| SCHEMBL7363053 | 0.76 | ECE1 (0.47) | RENKISS1RMMP8PTPN1 | |
| SCHEMBL7359768 | 0.76 | ECE1 (0.49) | RENMMP1FCER2KISS1RMMP8 | |
| SCHEMBL2914760 | 0.75 | CTSK (0.70) | PSMB1CTSKCTSLCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |