Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364892 | 1.00 | CTSK (0.47) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL16272898 | 0.81 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL5021049 | 0.79 | CTSB (0.49) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL27853178 | 0.75 | CTSK (0.48) | CTSKCTSBCTSSCTSLMAPT | |
| SCHEMBL13519510 | 0.75 | CTSK (0.48) | CTSKCTSBCTSSCTSLMAPT | |
| SCHEMBL9841061 | 0.75 | EPOR (0.50) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL2300007 | 0.75 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL2497060 | 0.75 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL7000046 | 0.75 | CTSK (0.57) | CTSKCTSBCTSSCTSLALDH1A1 | |
| SCHEMBL11704433 | 0.75 | CTSB (0.63) | CTSKCTSBCTSSCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |