Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364355 | 0.74 | CYP4F2 (0.42) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6298270 | 0.74 | HPGD (0.40) | ALDH1A1HPGDMEN1GLAMAPT | |
| SCHEMBL7358838 | 0.72 | LTB4R (0.35) | ALDH1A1HPGD | |
| SCHEMBL2229904 | 0.69 | — | — | |
| SCHEMBL12520102 | 0.69 | GABRA1 (0.39) | ALDH1A1MAPTHDAC6 | |
| SCHEMBL2969315 | 0.68 | — | — | |
| SCHEMBL7365129 | 0.68 | DPP4 (0.34) | DPP4 | |
| SCHEMBL28738267 | 0.67 | POLB (0.57) | ALDH1A1HPGDMEN1GLAMAPT | |
| SCHEMBL13545160 | 0.67 | HPGD (0.54) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31112245 | 0.67 | HPGD (0.54) | ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |