Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355294 | 0.87 | MTNR1A (0.58) | ATMSMN1; SMN2 | |
| SCHEMBL7598913 | 0.86 | ATM (0.60) | ATMPOLB | |
| SCHEMBL9654129 | 0.83 | PTGS1 (0.60) | ATMPOLBSMN1; SMN2 | |
| Methane SCHEMBL9655846 | 0.82 | PTGS1 (0.59) | ATMPOLBSMN1; SMN2 | |
| Methane SCHEMBL10588144 | 0.82 | PTGS1 (0.59) | ATMPOLBSMN1; SMN2 | |
| Methane SCHEMBL9654134 | 0.81 | PTGS1 (0.60) | ATMPOLBSMN1; SMN2 | |
| SCHEMBL7357729 | 0.80 | L3MBTL1 (0.66) | POLBMAPK1SMN1; SMN2 | |
| SCHEMBL5275656 | 0.77 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL7338221 | 0.77 | POLB (0.79) | ATMCNR1POLB | |
| SCHEMBL3904019 | 0.77 | ATM (0.58) | ATMMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996008463-A1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |