Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ERN1 | O75460 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293621 | 0.82 | ERN1 (0.68) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL4945362 | 0.80 | ALDH1A1 (0.60) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL15119999 | 0.80 | ALDH1A1 (0.66) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL27908987 | 0.79 | ERN1 (0.64) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL15883267 | 0.79 | ALDH1A1 (0.53) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL29459646 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL12311288 | 0.78 | ERN1 (0.65) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL1002582 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL1619656 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL13076862 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ERN1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240308968-A1 | FUNGICIDAL SUBSTITUTED HETEROCYCLES | FMC CORP (US) | 2024-09-19 | — | — | US | disclosed |
| EP-4387957-A1 | FUNGICIDAL SUBSTITUTED HETEROCYCLES | FMC Corporation (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-117836274-A | Fungicidal substituted heterocyclic compounds | FMC公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023023242-A1 | FUNGICIDAL SUBSTITUTED HETEROCYCLES | FMC CORPORATION (US) | 2023-02-23 | — | — | WO | disclosed |
| CN-111278823-B | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| US-20200253978-A1 | HETEROCYCLICS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | ADVNET PHARMA CO. LTD. (CN) | 2020-08-13 | — | — | US | disclosed |
| CN-111278823-A | Heterocyclic compounds as fibroblast growth factor receptor inhibitors | 上海新契博生物科技有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-108503593-A | 2- amino-metadiazine compounds and its application | 暨南大学 | 2018-09-07 | — | — | CN | disclosed |
| CN-102971316-A | Fused bicyclic kinase inhibitors | OSI PHARMACEUTICALS LLC | 2013-03-13 | — | — | CN | disclosed |
| US-8138340-B2 | Bicyclononene derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-03-20 | — | — | US | disclosed |
| CN-101010323-B | Bicyclononene derivatives as renin inhibitors | ACTELION PHARMACEUTICALS LTD | 2010-06-16 | — | — | CN | disclosed |
| EP-1786814-B1 | BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-03-31 | — | — | EP | disclosed |
| US-20090306123-A1 | Bicyclononene derivaties | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-12-10 | — | — | US | disclosed |
| CN-101010323-A | Bicyclononene derivatives as renin inhibitors | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-01 | — | — | CN | disclosed |
| EP-1786814-A1 | BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021402-A1 | BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD. (CH) | 2006-03-02 | — | — | WO | disclosed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200253978-A1 | HETEROCYCLICS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | FGFR1, FGFR4, FGFR2 | ALDH1A1 699/4885ERN1 3952/4885KDM4E 703/4885 |
| US-20090306123-A1 | Bicyclononene derivaties | REN, ACE, CYP51A1 | ALDH1A1 583/4885ERN1 2124/4885KDM4E 2801/4885 |
| US-20240308968-A1 | FUNGICIDAL SUBSTITUTED HETEROCYCLES | CYP1B1, CYP1A1, NOX1 | ALDH1A1 610/4885ERN1 2362/4885KDM4E 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.