Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 7/20 | 0.52 |
| ▸ | PRKDC | P78527 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064540 | 0.83 | ERN1 (0.48) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL15119999 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL12311288 | 0.82 | ERN1 (0.65) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1002582 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL29459646 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL736513 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1619656 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL120483 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL31274281 | 0.80 | TUBB4A (0.60) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL13076862 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| CN-111848954-B | Modified polyimide precursor resin, photosensitive resin composition and application thereof | 北京鼎材科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-111848954-A | Modified polyimide precursor resin, photosensitive resin composition and application thereof | 北京鼎材科技有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2018-06-21 | — | — | US | disclosed |
| US-9895361-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2016-06-30 | — | — | US | disclosed |
| US-9107874-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8496951-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2013-02-07 | — | — | US | disclosed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | disclosed |
| US-20030083504-A1 | N- (4-carbamimidoyl-phenyl) -glycine derivatives | ACKERMANN JEAN (CH) | 2003-05-01 | — | — | US | disclosed |
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | disclosed |
| US-6476264-B2 | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. | 2002-11-05 | — | — | US | disclosed |
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| US-6242644-B1 | FOR TREATING THROMBOSIS, APOPLEXY, CARDIAC INFARCTION, INFLAMATION AND ARTHEROSCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-06-05 | — | — | US | disclosed |
| US-20010001799-A1 | N-(4- carbamimidoyl-phenyl) -glycine derivatives | ACKERMANN JEAN (CH) | 2001-05-24 | — | — | US | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885KDM4E 2261/4885TSHR 4387/4885 |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885KDM4E 2261/4885TSHR 4387/4885 |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885KDM4E 2261/4885TSHR 4387/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | ALDH1A1 4/4885KDM4E 2261/4885TSHR 4387/4885 |
| US-20010001799-A1 | N-(4- carbamimidoyl-phenyl) -glycine derivatives | GLRA1, NGLY1, GLS | ALDH1A1 2850/4885KDM4E 1998/4885TSHR 3764/4885 |
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | ALDH1A1 88/4885KDM4E 1204/4885TSHR 1982/4885 |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | ALDH1A1 4/4885KDM4E 2261/4885TSHR 4387/4885 |
| US-20030083504-A1 | N- (4-carbamimidoyl-phenyl) -glycine derivatives | GLRA1, NGLY1, GLS | ALDH1A1 2850/4885KDM4E 1998/4885TSHR 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.