Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.57 |
| ▸ | KDM6B | O15054 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360063 | 0.86 | KDM6B (0.59) | BRS3KDM4CKDM6BKDM4EKDM4A | |
| SCHEMBL29377096 | 0.81 | HSD17B10 (0.55) | BRS3KDM4EHPGDMEN1ALDH1A1 | |
| SCHEMBL401444 | 0.81 | HSD17B10 (0.55) | BRS3KDM4EHPGDMEN1ALDH1A1 | |
| SCHEMBL28535503 | 0.80 | HSD17B10 (0.53) | BRS3KDM4EHPGDMEN1ALDH1A1 | |
| SCHEMBL28533341 | 0.80 | HSD17B10 (0.53) | BRS3KDM4EHPGDMEN1ALDH1A1 | |
| SCHEMBL7398435 | 0.78 | CA12 (0.47) | BRS3KDM4CKDM6BHPGDALDH1A1 | |
| SCHEMBL7366988 | 0.76 | F2 (0.55) | — | |
| SCHEMBL7366989 | 0.76 | F2 (0.55) | — | |
| SCHEMBL2511447 | 0.76 | KDM4C (0.78) | BRS3KDM4CKDM6BKDM4EKDM4A | |
| SCHEMBL7396131 | 0.75 | KDM6B (0.55) | BRS3KDM4CKDM6BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |