Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 4/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365224 | 0.86 | BRS3 (0.62) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7358606 | 0.77 | KDM4C (0.56) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7366380 | 0.77 | KDM4C (0.52) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7398435 | 0.76 | CA12 (0.47) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL3716882 | 0.75 | KDM4C (0.67) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7366989 | 0.74 | F2 (0.55) | — | |
| SCHEMBL7366988 | 0.74 | F2 (0.55) | — | |
| SCHEMBL7396131 | 0.72 | KDM6B (0.55) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL14627251 | 0.71 | PTGS1 (0.53) | — | |
| SCHEMBL7361470 | 0.71 | F2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |