Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398435 | 0.83 | CA12 (0.47) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7366380 | 0.78 | KDM4C (0.52) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7358606 | 0.78 | KDM4C (0.56) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL7365224 | 0.75 | BRS3 (0.62) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL14627251 | 0.74 | PTGS1 (0.53) | — | |
| SCHEMBL3712114 | 0.73 | KDM4C (0.62) | KDM6BKDM4CHCAR3HCAR2 | |
| SCHEMBL7360063 | 0.72 | KDM6B (0.59) | KDM6BKDM4CCA12CA1CA2 | |
| SCHEMBL14523123 | 0.69 | CA12 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8847131 | 0.68 | NAPRT (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28039977 | 0.68 | CA12 (0.44) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |