SCHEMBL7366989

SCHEMBL7366989

O=S(=O)(O)c1cnccc1N[C@H](CO)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.55
PRSS1 P07477 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7366988 1.00 F2 (0.55) F2PRSS1
SCHEMBL7361470 0.87 F2 (0.45) F2PRSS1
SCHEMBL7398186 0.81 F2 (0.58) F2PRSS1
SCHEMBL7398182 0.81 F2 (0.58) F2PRSS1
SCHEMBL7366504 0.79 KDM4E (0.48) F2PRSS1
SCHEMBL7365224 0.76 BRS3 (0.62)
SCHEMBL7360063 0.74 KDM6B (0.59)
SCHEMBL27503830 0.66 KMT2A (0.58)
SCHEMBL23211680 0.66 KDM4E (0.51)
SCHEMBL21410863 0.66 KDM4E (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997046553-A1 THROMBIN INHIBITORS NOVARTIS AG (CH) 1997-12-11 WO disclosed