Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344661 | 0.88 | MAPT (0.60) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL10889767 | 0.87 | MAPT (0.71) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7341670 | 0.85 | MAPT (0.60) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7369889 | 0.85 | ABCB1 (0.68) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7340809 | 0.84 | MAPT (0.57) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7327248 | 0.84 | HIF1A (0.65) | MAPTMEN1CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL7364760 | 0.84 | ADRA1A (0.57) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7428736 | 0.84 | MAPT (0.62) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7344588 | 0.83 | MAPT (0.59) | ADRA1AMAPTADRA2AADRA2BADRA2C | |
| SCHEMBL7329073 | 0.83 | CACNA1F (0.66) | MAPTMEN1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |