Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 6/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929786 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL5565559 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL19057143 | 0.69 | KMT2A (0.41) | MMP1ADAM17CTSSALDH1A1KMT2A | |
| SCHEMBL19472816 | 0.69 | KMT2A (0.41) | MMP1ADAM17CTSSALDH1A1KMT2A | |
| SCHEMBL11991369 | 0.68 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNANPSR1ADH1B | |
| SCHEMBL15491255 | 0.66 | MMP1 (0.36) | MMP1ADAM17CTSSALDH1A1KMT2A | |
| SCHEMBL20746810 | 0.66 | USP2 (0.40) | MMP1ADAM17CTSSALDH1A1KMT2A | |
| SCHEMBL11991361 | 0.66 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL5911087 | 0.65 | KMT2A (0.39) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL36573 | 0.65 | MAPT (0.39) | ALDH1A1KMT2ALMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558603-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| WO-1992008688-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | claimed |