SCHEMBL7365422

SCHEMBL7365422

CCSc1cccnc1C#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.40
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
CLK1 P49759 1/20 0.40
CYP11B1 P15538 1/20 0.39
USP8 P40818 1/20 0.38
PLCG1 P19174 1/20 0.38
MPO P05164 1/20 0.38
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7467210 0.82 HSD17B10 (0.38) HPGDALDH1A1KDM4ELMNACLK1
SCHEMBL24058185 0.81 XDH (0.36) HPGDALDH1A1KDM4ECYP11B1PLCG1
SCHEMBL6953445 0.79 GRM5 (0.42) HPGDALDH1A1CYP11B1PLCG1MPO
SCHEMBL7364820 0.79 PLCG1 (0.43) HPGDALDH1A1KDM4ECYP11B1PLCG1
SCHEMBL30023811 0.78 HSD17B10 (0.51) HPGDALDH1A1KDM4ELMNAMPO
SCHEMBL7363968 0.78 ALDH1A1 (0.38) HPGDALDH1A1KDM4ECYP11B1PLCG1
SCHEMBL17010338 0.78 HSD17B10 (0.51) HPGDALDH1A1KDM4ELMNAMPO
SCHEMBL24056578 0.77 AR (0.38) CYP11B1PLCG1MPOARHSD11B1
SCHEMBL3086616 0.75 PLCG1 (0.44) HPGDALDH1A1KDM4ECYP11B1PLCG1
SCHEMBL4611591 0.75 PLCG1 (0.38) HPGDALDH1A1KDM4ECYP11B1PLCG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724425-A1 SYNTHESIS OF ENANTIOENRICHED 2-CYANO PYRIDYL SULFOXIDES Syngenta Crop Protection AG (CH) 2026-04-15 EP disclosed
WO-2025061707-A1 SYNTHESIS OF SULFOXIMINES CONTAINING A BENZIMIDAZOLE MOIETY SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 WO disclosed
WO-2024251913-A1 SYNTHESIS OF ENANTIOENRICHED 2-CYANO PYRIDYL SULFOXIDES SYNGENTA CROP PROTECTION AG (CH) 2024-12-12 WO disclosed
EP-3931187-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2023-10-18 EP disclosed
US-20230192683-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GUANGZHOU FERMION TECHNOLOGY CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192683-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF GUANGZHOU FERMION TECHNOLOGY CO., LTD. (CN) 2023-06-22 US disclosed
CN-115991703-A Ring-fused compound, preparation method thereof, pharmaceutical composition and application 广州费米子科技有限责任公司 2023-04-21 CN disclosed
EP-4155305-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF Guangzhou Fermion Technology Co., Ltd. (CN) 2023-03-29 EP disclosed
CN-113717167-B Fused ring compound, preparation method thereof, pharmaceutical composition and application 广州费米子科技有限责任公司 2022-12-02 CN disclosed
US-20220144799-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 US disclosed
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-05 US disclosed
EP-2938601-A1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Company Limited (JP) 2015-11-04 EP disclosed
US-20150189880-A1 AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-09 US disclosed
US-20150189880-A1 AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-09 US disclosed
EP-2881386-A1 AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2015-06-10 EP disclosed
WO-2014123205-A1 CONDENSED HETEROCYCLIC COMPOUND 住友化学株式会社 (JP) 2014-08-14 WO disclosed
WO-2014104407-A1 FUSED OXAZOLE COMPOUNDS AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 WO disclosed
EP-1259506-A1 PYRAZINONE THROMBIN INHIBITORS Merck & Co., Inc. (US) 2002-11-27 EP disclosed
US-6387911-B1 Pyrazinone thrombin inhibitors MERCK & CO., INC. 2002-05-14 US disclosed
WO-2001038323-A1 PYRAZINONE THROMBIN INHIBITORS MERCK & CO., INC. (US) 2001-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150189880-A1 AMIDE COMPOUND H1-3, H1-0, H1-4 HPGD 2129/4885ALDH1A1 2524/4885KDM4E 2243/4885
US-20150313234-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL AFF1, AFF2, PYM1 HPGD 3739/4885ALDH1A1 1355/4885KDM4E 2940/4885
US-20230192683-A1 FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF SSTR4, SSTR3, NPY4R HPGD 3345/4885ALDH1A1 3727/4885KDM4E 2865/4885
US-20220144799-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS ACHE, DDT, AADAC HPGD 1178/4885ALDH1A1 102/4885KDM4E 1666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.