Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 11/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.43 |
| ▸ | PDE4A | P27815 | 8/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361173 | 0.85 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7368427 | 0.85 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7053201 | 0.81 | PDE4A (0.60) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL6605574 | 0.80 | PDE4A (0.47) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL7050225 | 0.78 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL3924757 | 0.77 | KDM4E (0.49) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL3931673 | 0.77 | PDE4A (0.45) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL3922215 | 0.76 | PPARG (0.44) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL7433190 | 0.74 | PDE4D (0.41) | PDE4DPDE4BPDE4APDE4CCA12 | |
| SCHEMBL73952 | 0.74 | ALDH1A1 (0.47) | PDE4DPDE4BPDE4APDE4CCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901482-A1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044337-A1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1997-11-27 | — | — | WO | disclosed |