Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.42 |
| ▸ | PDE4A | P27815 | 12/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361173 | 1.00 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7365432 | 0.85 | PDE4D (0.43) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7049311 | 0.76 | PDE4A (0.56) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7054770 | 0.75 | PDE4A (0.46) | PDE4DPDE4BPDE4APDE4CALDH1A1 | |
| SCHEMBL7054767 | 0.75 | PDE4A (0.46) | PDE4DPDE4BPDE4APDE4CALDH1A1 | |
| SCHEMBL7054773 | 0.75 | PDE4A (0.46) | PDE4DPDE4BPDE4APDE4CALDH1A1 | |
| SCHEMBL7361170 | 0.74 | PDE4D (0.39) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL74713 | 0.72 | PDE4A (0.49) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL7050225 | 0.69 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CKDM4E | |
| SCHEMBL5388885 | 0.68 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |