Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.32 |
| ▸ | HTR3B | O95264 | 2/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7363350 | 0.99 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2POLBTSHR | |
| SCHEMBL7355302 | 0.86 | TSHR (0.35) | POLBTSHRHSD11B1HTR4 | |
| Hydrochloric Acid SCHEMBL7365195 | 0.84 | TSHR (0.34) | POLBTSHRHSD11B1HTR4 | |
| SCHEMBL7436836 | 0.74 | MAOA (0.35) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7355305 | 0.74 | HTR4 (0.39) | HTR4HTR3AHTR1AADRA2CACHE | |
| Hydrochloric Acid SCHEMBL7361122 | 0.73 | HTR4 (0.39) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL7430275 | 0.72 | PARP1 (0.49) | HSD11B1 | |
| SCHEMBL7365599 | 0.72 | HTR4 (0.41) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7363354 | 0.71 | HTR4 (0.40) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7360909 | 0.67 | HTR4 (0.52) | SLC6A4SLC6A3SLC6A2TSHRHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | disclosed |