Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7365195 | 0.98 | TSHR (0.34) | TSHRPOLBHSD11B1MEN1ALDH1A1 | |
| SCHEMBL7365597 | 0.86 | SLC6A4 (0.34) | TSHRPOLBHSD11B1HTR4 | |
| Hydrochloric Acid SCHEMBL7363350 | 0.85 | SLC6A4 (0.34) | TSHRPOLBHSD11B1LMNAHTR4 | |
| SCHEMBL7430275 | 0.75 | PARP1 (0.49) | HSD11B1ALDH1A1 | |
| SCHEMBL7355305 | 0.74 | HTR4 (0.39) | MEN1ALDH1A1KMT2AHTR4 | |
| Hydrochloric Acid SCHEMBL7361122 | 0.73 | HTR4 (0.39) | MEN1ALDH1A1LMNAKMT2AHTR4 | |
| SCHEMBL7365599 | 0.72 | HTR4 (0.41) | MEN1ALDH1A1KMT2AHTR4 | |
| SCHEMBL7436836 | 0.72 | MAOA (0.35) | KMT2AHTR4 | |
| Hydrochloric Acid SCHEMBL7363354 | 0.72 | HTR4 (0.40) | MEN1ALDH1A1LMNAKMT2AHTR4 | |
| SCHEMBL7326376 | 0.69 | HSD11B1 (0.36) | HSD11B1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | claimed |
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | disclosed |